The final stage opened at a relentless pace, with repeated attacks before a large, dangerous breakaway formed — Tom Pidcock, Stage 4 winner Lennart Jasch, Sam Oomen and Koen Bouwman among them. The move built over two minutes, briefly putting Juan Felipe Rodriguez into the virtual race lead and forcing Red Bull - BORA - hansgrohe to defend Pellizzari's slender four-second cushion. On the 12.7 km climb to Nobls/Montoppio the break shattered and was reeled in, with Pidcock and Rodriguez among the last caught. Pellizzari then attacked from the reduced group, immediately separating from Arensman and Bernal. Behind, Michael Storer raised the pace; Bernal followed but Arensman couldn't respond and lost ground — the split that reshaped the podium. Pellizzari crested the climb alone and extended his lead on the descent to win the stage by around 30 seconds, converting his overnight lead into a clear overall victory.

Pellizzari sealed the maiden GC win of his career, finishing 40 seconds clear of Egan Bernal and 50 seconds ahead of Thymen Arensman in the final general classification. Michael Storer was fourth at +1:09 and Tudor's Mathys Rondel fifth at +1:45, with Aleksandr Vlasov sixth and Pidcock seventh. Pellizzari also took the youth classification; the points jersey went to Tommaso Dati and the mountains jersey to Lennart Jasch, with Red Bull - BORA - hansgrohe winning the team classification.